Nick: https://scholar.google.com/citations?user=HrhaGAgAAAAJ&hl=en&oi=ao

Nathan: https://scholar.google.com/citations?hl=en&user=ehIrtGsAAAAJ

1: Arvanitis CD, Livingstone MS, McDannold N. Combined ultrasound and MR imaging to guide focused ultrasound therapies in the brain. Phys Med Biol. 2013 Jul 21;58(14):4749-61. doi: 10.1088/0031-9155/58/14/4749. Epub 2013 Jun 20. PubMed PMID: 23788054.

2: Aryal M, Vykhodtseva N, Zhang YZ, Park J, McDannold N. Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood-tumor and blood-brain barriers improve outcomes in a rat glioma model. J Control Release. 2013 Jul 10;169(1-2):103-11. doi: 10.1016/j.jconrel.2013.04.007. Epub 2013 Apr 18. PubMed PMID: 23603615.

3: Schwartz BM, McDannold NJ. Ultrasound echoes as biometric navigators. Magn Reson Med. 2013 Apr;69(4):1023-33. doi: 10.1002/mrm.24336. Epub 2012 May 30. PubMed PMID: 22648783.

4: Kamakura T, Nomura H, Clement GT. Application of the split-step Padé approach to nonlinear field predictions. Ultrasonics. 2013 Feb;53(2):432-8. doi: 10.1016/j.ultras.2012.08.008. Epub 2012 Oct 3. PubMed PMID: 23099121.

5: Kopechek JA, Park E, Mei CS, McDannold NJ, Porter TM. Accumulation of phase-shift nanoemulsions to enhance MR-guided ultrasound-mediated tumor ablation in vivo. J Healthc Eng. 2013;4(1):109-26. doi: 10.1260/2040-2295.4.1.109. PubMed PMID: 23502252.

6: Park EJ, Zhang YZ, Vykhodtseva N, McDannold N. Ultrasound-mediated blood-brain/blood-tumor barrier disruption improves outcomes with trastuzumab in a breast cancer brain metastasis model. J Control Release. 2012 Nov 10;163(3):277-84. doi: 10.1016/j.jconrel.2012.09.007. Epub 2012 Sep 18. PubMed PMID: 23000189; PubMed Central PMCID: PMC3502612.

7: Treat LH, McDannold N, Zhang Y, Vykhodtseva N, Hynynen K. Improved anti-tumor effect of liposomal doxorubicin after targeted blood-brain barrier disruption by MRI-guided focused ultrasound in rat glioma. Ultrasound Med Biol. 2012 Oct;38(10):1716-25. doi: 10.1016/j.ultrasmedbio.2012.04.015. Epub 2012 Jul 19. PubMed PMID: 22818878; PubMed Central PMCID: PMC3438387.

8: Park J, Zhang Y, Vykhodtseva N, Jolesz FA, McDannold NJ. The kinetics of blood brain barrier permeability and targeted doxorubicin delivery into brain induced by focused ultrasound. J Control Release. 2012 Aug 20;162(1):134-42. doi: 10.1016/j.jconrel.2012.06.012. Epub 2012 Jun 15. PubMed PMID: 22709590; PubMed Central PMCID: PMC3520430.

9: Jing Y, Wang T, Clement GT. A k-space method for moderately nonlinear wave propagation. IEEE Trans Ultrason Ferroelectr Freq Control. 2012 Aug;59(8):1664-73. doi: 10.1109/TUFFC.2012.2372. PubMed PMID: 22899114.

10: McDannold N, Arvanitis CD, Vykhodtseva N, Livingstone MS. Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques. Cancer Res. 2012 Jul 15;72(14):3652-63. doi: 10.1158/0008-5472.CAN-12-0128. Epub 2012 May 2. PubMed PMID: 22552291; PubMed Central PMCID: PMC3533365.

11: Jing Y, Meral FC, Clement GT. Time-reversal transcranial ultrasound beam focusing using a k-space method. Phys Med Biol. 2012 Feb 21;57(4):901-17. doi: 10.1088/0031-9155/57/4/901. Epub 2012 Jan 31. PubMed PMID: 22290477; PubMed Central PMCID: PMC3366238.

12: Mei CS, Mulkern RV, Oshio K, Chen NK, Madore B, Panych LP, Hynynen K, McDannold NJ. Ultrafast 1D MR thermometry using phase or frequency mapping. MAGMA. 2012 Feb;25(1):5-14. doi: 10.1007/s10334-011-0272-9. Epub 2011 Jul 29. PubMed PMID: 21800192; PubMed Central PMCID: PMC3245381.

13: Arvanitis CD, Livingstone MS, Vykhodtseva N, McDannold N. Controlled ultrasound-induced blood-brain barrier disruption using passive acoustic emissions monitoring. PLoS One. 2012;7(9):e45783. doi: 10.1371/journal.pone.0045783. Epub 2012 Sep 24. PubMed PMID: 23029240; PubMed Central PMCID: PMC3454363.

14: Park J, Zhang Y, Vykhodtseva N, Akula JD, McDannold NJ. Targeted and reversible blood-retinal barrier disruption via focused ultrasound and microbubbles. PLoS One. 2012;7(8):e42754. doi: 10.1371/journal.pone.0042754. Epub 2012 Aug 13. PubMed PMID: 22912733; PubMed Central PMCID: PMC3418291.

15: Yuan J, Mei CS, Panych LP, McDannold NJ, Madore B. Towards fast and accurate temperature mapping with proton resonance frequency-based MR thermometry. Quant Imaging Med Surg. 2012;2(1):21-32. PubMed PMID: 22773966; PubMed Central PMCID: PMC3389756.

16: Aljallad MH, Yuan J, Pilatou MC, McDannold NJ, Panych LP. Multiresolution MRI temperature monitoring in a reduced field of view. Magn Reson Imaging. 2011 Nov;29(9):1205-14. doi: 10.1016/j.mri.2011.07.020. Epub 2011 Sep 9. PubMed PMID: 21908128; PubMed Central PMCID: PMC3199290.

17: Clement GT, Nomura H, Kamakura T. The feasibility of pulse compression by nonlinear effective bandwidth extension. J Acoust Soc Am. 2011 Oct;130(4):1810-9. doi: 10.1121/1.3625236. PubMed PMID: 21973334.

18: Jing Y, Clement GT. On the use of Gegenbauer reconstructions for shock wave propagation modeling. J Acoust Soc Am. 2011 Sep;130(3):1115-24. doi: 10.1121/1.3621485. PubMed PMID: 21895054; PubMed Central PMCID: PMC3188966.

19: McDannold N, Zhang Y, Vykhodtseva N. Blood-brain barrier disruption and vascular damage induced by ultrasound bursts combined with microbubbles can be influenced by choice of anesthesia protocol. Ultrasound Med Biol. 2011 Aug;37(8):1259-70. doi: 10.1016/j.ultrasmedbio.2011.04.019. Epub 2011 Jun 8.
PubMed PMID: 21645965; PubMed Central PMCID: PMC3129385.

20: Mei CS, Panych LP, Yuan J, McDannold NJ, Treat LH, Jing Y, Madore B. Combining two-dimensional spatially selective RF excitation, parallel imaging, and UNFOLD for accelerated MR thermometry imaging. Magn Reson Med. 2011 Jul;66(1):112-22. doi: 10.1002/mrm.22788. Epub 2011 Feb 17. PubMed PMID: 21337421; PubMed Central PMCID: PMC3120911.

21: Tang SC, Jolesz FA, Clement GT. A wireless batteryless deep-seated implantable ultrasonic pulser-receiver powered by magnetic coupling. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Jun;58(6):1211-21. doi: 10.1109/TUFFC.2011.1931. PubMed PMID: 21693403.

22: Yoo SS, Bystritsky A, Lee JH, Zhang Y, Fischer K, Min BK, McDannold NJ, Pascual-Leone A, Jolesz FA. Focused ultrasound modulates region-specific brain activity. Neuroimage. 2011 Jun 1;56(3):1267-75. doi:
10.1016/j.neuroimage.2011.02.058. Epub 2011 Feb 24. PubMed PMID: 21354315; PubMed Central PMCID: PMC3342684.

23: Jing Y, Shen D, Clement GT. Verification of the Westervelt equation for focused transducers. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 May;58(5):1097-101. doi: 10.1109/TUFFC.2011.1910. PubMed PMID: 21622065.

24: Yuan J, Mei CS, Madore B, McDannold NJ, Panych LP. Fast fat-suppressed reduced field-of-view temperature mapping using 2DRF excitation pulses. J Magn Reson. 2011 May;210(1):38-43. doi: 10.1016/j.jmr.2011.02.004. Epub 2011 Mar 2. PubMed PMID: 21371923; PubMed Central PMCID: PMC3085949.

25: Paltiel HJ, Padua HM, Gargollo PC, Cannon GM Jr, Alomari AI, Yu R, Clement GT. Contrast-enhanced, real-time volumetric ultrasound imaging of tissue perfusion: preliminary results in a rabbit model of testicular torsion. Phys Med Biol. 2011 Apr 7;56(7):2183-97. doi: 10.1088/0031-9155/56/7/018. Epub 2011 Mar 14. PubMed PMID: 21403185.

26: Tempany CM, McDannold NJ, Hynynen K, Jolesz FA. Focused ultrasound surgery in oncology: overview and principles. Radiology. 2011 Apr;259(1):39-56. doi: 10.1148/radiol.11100155. Review. PubMed PMID: 21436096; PubMed Central PMCID: PMC3064817.

27: Jing Y, Tao M, Clement GT. Evaluation of a wave-vector-frequency-domain method for nonlinear wave propagation. J Acoust Soc Am. 2011 Jan;129(1):32-46. doi: 10.1121/1.3504705. PubMed PMID: 21302985; PubMed Central PMCID: PMC3055284.

28: Clement GT. Spatial backward planar projection in absorbing media possessing an arbitrary dispersion relation. Acoust Sci Technol. 2010 Nov 1;31(6):379-386. PubMed PMID: 21611135; PubMed Central PMCID: PMC3099221.

29: McDannold N, Park EJ, Mei CS, Zadicario E, Jolesz F. Evaluation of three-dimensional temperature distributions produced by a low-frequency transcranial focused ultrasound system within ex vivo human skulls. IEEE Trans Ultrason Ferroelectr Freq Control. 2010 Sep;57(9):1967-76. doi: 10.1109/TUFFC.2010.1644. PubMed PMID: 20875986; PubMed Central PMCID: PMC3101627.

30: McDannold N, Clement GT, Black P, Jolesz F, Hynynen K. Transcranial magnetic resonance imaging- guided focused ultrasound surgery of brain tumors: initial findings in 3 patients. Neurosurgery. 2010 Feb;66(2):323-32; discussion 332. doi: 10.1227/01.NEU.0000360379.95800.2F. PubMed PMID: 20087132; PubMed Central PMCID: PMC2939497.

31: Tang SC, Clement GT. Standing-wave suppression for transcranial ultrasound by random modulation. IEEE Trans Biomed Eng. 2010 Jan;57(1):203-5. doi: 10.1109/TBME.2009.2028653. Epub 2009 Aug 18. PubMed PMID: 19695991; PubMed Central PMCID: PMC2887681.

32: Madore B, White PJ, Thomenius K, Clement GT. Accelerated focused ultrasound imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2009 Dec;56(12):2612-23. doi: 10.1109/TUFFC.2009.1352. PubMed PMID: 20040398; PubMed Central PMCID: PMC2813841.

33: Fischer K, McDannold NJ, Zhang Y, Kardos M, Szabo A, Szabo A, Reusz GS, Jolesz FA. Renal ultrafiltration changes induced by focused US. Radiology. 2009 Dec;253(3):697-705. doi: 10.1148/radiol.2532082100. Epub 2009 Jul 31. PubMed PMID: 19703861; PubMed Central PMCID: PMC2786196.

34: Farny CH, Clement GT. Ultrasound phase contrast thermal imaging with reflex transmission imaging methods in tissue phantoms. Ultrasound Med Biol. 2009 Dec;35(12):1995-2006. doi: 10.1016/j.ultrasmedbio.2009.05.019. Epub 2009 Aug 14. PubMed PMID: 19683380; PubMed Central PMCID: PMC2790025.

35: Taran FA, Tempany CM, Regan L, Inbar Y, Revel A, Stewart EA; MRgFUS Group. Magnetic resonance-guided focused ultrasound (MRgFUS) compared with abdominal hysterectomy for treatment of uterine leiomyomas. Ultrasound Obstet Gynecol. 2009 Nov;34(5):572-8. doi: 10.1002/uog.7435. PubMed PMID: 19852046.

36: Tang SC, Clement GT. Acoustic standing wave suppression using randomized phase-shift-keying excitations. J Acoust Soc Am. 2009 Oct;126(4):1667-70. doi: 10.1121/1.3203935. PubMed PMID: 19813782; PubMed Central PMCID: PMC2771052.

37: Shen SH, Fennessy F, McDannold N, Jolesz F, Tempany C. Image-guided thermal therapy of uterine fibroids. Semin Ultrasound CT MR. 2009 Apr;30(2):91-104. Review. PubMed PMID: 19358440; PubMed Central PMCID: PMC2768544.

38: Pilatou MC, Stewart EA, Maier SE, Fennessy FM, Hynynen K, Tempany CM, McDannold N. MRI-based thermal dosimetry and diffusion-weighted imaging of MRI-guided focused ultrasound thermal ablation of uterine fibroids. J Magn Reson Imaging. 2009 Feb;29(2):404-11. doi: 10.1002/jmri.21688. PubMed PMID: 19161196; PubMed Central PMCID: PMC2754252.

39: White PJ, Whalen S, Tang SC, Clement GT, Jolesz F, Golby AJ. An intraoperative brain shift monitor using shear mode transcranial ultrasound: preliminary results. J Ultrasound Med. 2009 Feb;28(2):191-203. PubMed PMID: 19168769; PubMed Central PMCID: PMC2631551.

40: McDannold N, Tempany C, Jolesz F, Hynynen K. Evaluation of referenceless thermometry in MRI-guided focused ultrasound surgery of uterine fibroids. J Magn Reson Imaging. 2008 Oct;28(4):1026-32. doi: 10.1002/jmri.21506. PubMed PMID: 18821603; PubMed Central PMCID: PMC2574694.

41: Lénárd ZM, McDannold NJ, Fennessy FM, Stewart EA, Jolesz FA, Hynynen K, Tempany CM. Uterine leiomyomas: MR imaging-guided focused ultrasound surgery–imaging predictors of success. Radiology. 2008 Oct;249(1):187-94. doi: 10.1148/radiol.2491071600. Epub 2008 Aug 11. PubMed PMID: 18695211; PubMed Central PMCID: PMC2657858.

42: McDannold N, Maier SE. Magnetic resonance acoustic radiation force imaging. Med Phys. 2008 Aug;35(8):3748-58. PubMed PMID: 18777934; PubMed Central PMCID: PMC2673647.

43: Vykhodtseva N, McDannold N, Hynynen K. Progress and problems in the application of focused ultrasound for blood-brain barrier disruption. Ultrasonics. 2008 Aug;48(4):279-96. doi: 10.1016/j.ultras.2008.04.004. Epub 2008 Apr 14. Review. PubMed PMID: 18511095; PubMed Central PMCID: PMC2569868.

44: Sheikov N, McDannold N, Sharma S, Hynynen K. Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium. Ultrasound Med Biol. 2008 Jul;34(7):1093-104. doi: 10.1016/j.ultrasmedbio.2007.12.015. Epub 2008 Apr 18. PubMed PMID: 18378064; PubMed Central PMCID: PMC2518085.

45: McDannold N, Vykhodtseva N, Hynynen K. Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption. Ultrasound Med Biol. 2008 Jun;34(6):930-7. doi: 10.1016/j.ultrasmedbio.2007.11.009. Epub 2008 Feb 21. PubMed PMID: 18294757; PubMed Central PMCID: PMC2459318.

46: Raymond SB, Treat LH, Dewey JD, McDannold NJ, Hynynen K, Bacskai BJ. Ultrasound enhanced delivery of molecular imaging and therapeutic agents in Alzheimer’s disease mouse models. PLoS One. 2008 May 14;3(5):e2175. doi: 10.1371/journal.pone.0002175. PubMed PMID: 18478109; PubMed Central PMCID: PMC2364662.

47: McDannold N, Vykhodtseva N, Hynynen K. Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index. Ultrasound Med Biol. 2008 May;34(5):834-40. doi: 10.1016/j.ultrasmedbio.2007.10.016. Epub 2008 Jan 22. PubMed PMID: 18207311; PubMed Central PMCID: PMC2442477.

48: Farny CH, Clement GT. Feasibility of ultrasound phase contrast for heating localization. J Acoust Soc Am. 2008 Mar;123(3):1773-83. doi: 10.1121/1.2835438. PubMed PMID: 18345865.

49: Tang SC, Clement GT. A harmonic cancellation technique for an ultrasound transducer excited by a switched-mode power converter. IEEE Trans Ultrason Ferroelectr Freq Control. 2008 Feb;55(2):359-67. doi: 10.1109/TUFFC.2008.654. Erratum in: IEEE Trans Ultrason Ferroelectr Freq Control. 2008 Mar;55(3):738. PubMed PMID: 18334342.

50: Jolesz FA, McDannold N. Current status and future potential of MRI-guided focused ultrasound surgery. J Magn Reson Imaging. 2008 Feb;27(2):391-9. doi: 10.1002/jmri.21261. Review. PubMed PMID: 18219674.

51: Pichardo S, Hynynen K. Treatment of near-skull brain tissue with a focused device using shear-mode conversion: a numerical study. Phys Med Biol. 2007 Dec 21;52(24):7313-32. Epub 2007 Dec 5. PubMed PMID: 18065841.

52: McDannold N, Barnes AS, Rybicki FJ, Oshio K, Chen NK, Hynynen K, Mulkern RV. Temperature mapping considerations in the breast with line scan echo planar spectroscopic imaging. Magn Reson Med. 2007 Dec;58(6):1117-23. PubMed PMID: 18046702.

53: White PJ, Clement GT. Two-dimensional localization with a single diffuse ultrasound field excitation. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Nov;54(11):2309-17. PubMed PMID: 18051165.

54: Tang SC, Clement GT, Hynynen K. A computer-controlled ultrasound pulser-receiver system for transskull fluid detection using a shear wave transmission technique. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Sep;54(9):1772-83. PubMed PMID: 17941383; PubMed Central PMCID: PMC2186207.

55: Treat LH, McDannold N, Vykhodtseva N, Zhang Y, Tam K, Hynynen K. Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound. Int J Cancer. 2007 Aug 15;121(4):901-7. PubMed PMID: 17437269.

56: White PJ, Palchaudhuri S, Hynynen K, Clement GT. The effects of desiccation on skull bone sound speed in porcine models. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Aug;54(8):1708-10. PubMed PMID: 17703676.

57: Fennessy FM, Tempany CM, McDannold NJ, So MJ, Hesley G, Gostout B, Kim HS, Holland GA, Sarti DA, Hynynen K, Jolesz FA, Stewart EA. Uterine leiomyomas: MR imaging-guided focused ultrasound surgery–results of different treatment protocols. Radiology. 2007 Jun;243(3):885-93. Epub 2007 Apr 19. PubMed PMID: 17446521.

58: McDannold N, Vykhodtseva N, Hynynen K. Use of ultrasound pulses combined with Definity for targeted blood-brain barrier disruption: a feasibility study. Ultrasound Med Biol. 2007 Apr;33(4):584-90. PubMed PMID: 17337109; PubMed Central PMCID: PMC2066193.

59: Hynynen K, Clement G. Clinical applications of focused ultrasound-the brain. Int J Hyperthermia. 2007 Mar;23(2):193-202. Review. PubMed PMID: 17578343.

60: Clement GT. Two-dimensional ultrasound detection with unfocused frequency-randomized signals. J Acoust Soc Am. 2007 Jan;121(1):636-47. PubMed PMID: 17297817; PubMed Central PMCID: PMC1839069.

61: Vykhodtseva N, McDannold N, Hynynen K. Induction of apoptosis in vivo in the rabbit brain with focused ultrasound and Optison. Ultrasound Med Biol. 2006 Dec;32(12):1923-9. PubMed PMID: 17169704.

62: McDannold N, Hynynen K. Quality assurance and system stability of a clinical MRI-guided focused ultrasound system: four-year experience. Med Phys. 2006 Nov;33(11):4307-13. PubMed PMID: 17153409.

63: McDannold NJ, Vykhodtseva NI, Hynynen K. Microbubble contrast agent with focused ultrasound to create brain lesions at low power levels: MR imaging and histologic study in rabbits. Radiology. 2006 Oct;241(1):95-106. PubMed PMID: 16990673.

64: Dimaio SP, Archip N, Hata N, Talos IF, Warfield SK, Majumdar A, Mcdannold N, Hynynen K, Morrison PR, Wells WM 3rd, Kacher DF, Ellis RE, Golby AJ, Black PM, Jolesz FA, Kikinis R. Image-guided neurosurgery at Brigham and Women’s Hospital. IEEE Eng Med Biol Mag. 2006 Sep-Oct;25(5):67-73. PubMed PMID: 17020201.

65: Hynynen K, McDannold N, Vykhodtseva N, Raymond S, Weissleder R, Jolesz FA, Sheikov N. Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg. 2006 Sep;105(3):445-54. PubMed PMID: 16961141.

66: Sheikov N, McDannold N, Jolesz F, Zhang YZ, Tam K, Hynynen K. Brain arterioles show more active vesicular transport of blood-borne tracer molecules than capillaries and venules after focused ultrasound-evoked opening of the blood-brain barrier. Ultrasound Med Biol. 2006 Sep;32(9):1399-409. PubMed PMID: 16965980.

67: So MJ, Fennessy FM, Zou KH, McDannold N, Hynynen K, Jolesz FA, Stewart EA, Rybicki FJ, Tempany CM. Does the phase of menstrual cycle affect MR-guided focused ultrasound surgery of uterine leiomyomas? Eur J Radiol. 2006 Aug;59(2):203-7. PubMed PMID: 16766153.

68: Hynynen K, McDannold N, Clement G, Jolesz FA, Zadicario E, Killiany R, Moore T, Rosen D. Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain–a primate study. Eur J Radiol. 2006 Aug;59(2):149-56. Epub 2006 May 23. PubMed PMID: 16716552.

69: Kinoshita M, McDannold N, Jolesz FA, Hynynen K. Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11719-23. Epub 2006 Jul 25. PubMed PMID: 16868082; PubMed Central
PMCID: PMC1544236.

70: Thierman JS, Clement GT, Kalish LA, O’Kane PL, Frauscher F, Paltiel HJ. Automated sonographic evaluation of testicular perfusion. Phys Med Biol. 2006 Jul 21;51(14):3419-32. Epub 2006 Jun 26. PubMed PMID: 16825740.

71: McDannold N, Tempany CM, Fennessy FM, So MJ, Rybicki FJ, Stewart EA, Jolesz FA, Hynynen K. Uterine leiomyomas: MR imaging-based thermometry and thermal dosimetry during focused ultrasound thermal ablation. Radiology. 2006 Jul;240(1):263-72. PubMed PMID: 16793983; PubMed Central PMCID: PMC1850234.

72: White PJ, Clement GT, Hynynen K. Longitudinal and shear mode ultrasound propagation in human skull bone. Ultrasound Med Biol. 2006 Jul;32(7):1085-96. PubMed PMID: 16829322; PubMed Central PMCID: PMC1560344.

73: White PJ, Clement GT, Hynynen K. Local frequency dependence in transcranial ultrasound transmission. Phys Med Biol. 2006 May 7;51(9):2293-305. Epub 2006 Apr 19. PubMed PMID: 16625043; PubMed Central PMCID: PMC1560343.

74: Kinoshita M, McDannold N, Jolesz FA, Hynynen K. Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound. Biochem Biophys Res Commun. 2006 Feb 24;340(4):1085-90. Epub 2005 Dec 27. PubMed PMID: 16403441.

75: McDannold N, Vykhodtseva N, Hynynen K. Targeted disruption of the blood-brain barrier with focused ultrasound: association with cavitation activity. Phys Med Biol. 2006 Feb 21;51(4):793-807. Epub 2006 Jan 25. PubMed PMID: 16467579.

76: Clement GT. Spectral image reconstruction for transcranial ultrasound measurement. Phys Med Biol. 2005 Dec 7;50(23):5557-72. Epub 2005 Nov 16. PubMed PMID: 16306652; PubMed Central PMCID: PMC1839070.

77: Clement GT, Huttunen J, Hynynen K. Superresolution ultrasound imaging using back-projected reconstruction. J Acoust Soc Am. 2005 Dec;118(6):3953-60. PubMed PMID: 16419839.

78: McDannold N, Vykhodtseva N, Raymond S, Jolesz FA, Hynynen K. MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits. Ultrasound Med Biol. 2005 Nov;31(11):1527-37. PubMed PMID: 16286030.

79: White J, Clement GT, Hynynen K. Transcranial ultrasound focus reconstruction with phase and amplitude correction. IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Sep;52(9):1518-22. PubMed PMID: 16285450.

80: McDannold N. Quantitative MRI-based temperature mapping based on the proton resonant frequency shift: review of validation studies. Int J Hyperthermia. 2005 Sep;21(6):533-46. Review. PubMed PMID: 16147438.

81: Clement GT, White PJ, King RL, McDannold N, Hynynen K. A magnetic resonance imaging-compatible, large-scale array for trans-skull ultrasound surgery and therapy. J Ultrasound Med. 2005 Aug;24(8):1117-25. PubMed PMID: 16040827.

82: Jolesz FA, Hynynen K, McDannold N, Tempany C. MR imaging-controlled focused ultrasound ablation: a noninvasive image-guided surgery. Magn Reson Imaging Clin N Am. 2005 Aug;13(3):545-60. Review. PubMed PMID: 16084419.

83: Silcox CE, Smith RC, King R, McDannold N, Bromley P, Walsh K, Hynynen K. MRI-guided ultrasonic heating allows spatial control of exogenous luciferase in canine prostate. Ultrasound Med Biol. 2005 Jul;31(7):965-70. PubMed PMID: 15972202.

84: Aarnio J, Clement GT, Hynynen K. A new ultrasound method for determining the acoustic phase shifts caused by the skull bone. Ultrasound Med Biol. 2005 Jun;31(6):771-80. PubMed PMID: 15936493.

85: Liu HL, McDannold N, Hynynen K. Focal beam distortion and treatment planning in abdominal focused ultrasound surgery. Med Phys. 2005 May;32(5):1270-80. PubMed PMID: 15984679.

86: Clement GT, Hynynen K. Ultrasound phase-contrast transmission imaging of localized thermal variation and the identification of fat/tissue boundaries. Phys Med Biol. 2005 Apr 7;50(7):1585-600. Epub 2005 Mar 22. PubMed PMID: 15798345.

87: Hynynen K, McDannold N, Sheikov NA, Jolesz FA, Vykhodtseva N. Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications. Neuroimage. 2005 Jan 1;24(1):12-20. PubMed PMID: 15588592.

88: Hindley J, Gedroyc WM, Regan L, Stewart E, Tempany C, Hynyen K, Mcdannold N, Inbar Y, Itzchak Y, Rabinovici J, Kim HS, Geschwind JF, Hesley G, Gostout B, Ehrenstein T, Hengst S, Sklair-Levy M, Shushan A, Jolesz F. MRI guidance of focused ultrasound therapy of uterine fibroids: early results. AJR Am J Roentgenol. 2004 Dec;183(6):1713-9. Erratum in: AJR Am J Roentgenol. 2005 Jan;184(1):348. Hynnen, Kullvro [corrected to Hynyen, Kullervo]; Macdanold, Nathan [corrected to Mcdannold, Nathan]; Kim, Kevin [corrected to Kim, Hyun S]; Gostout, Brian [corrected to Gostout, Bobbie]. PubMed PMID: 15547216.

89: Jolesz FA, Hynynen K, McDannold N, Freundlich D, Kopelman D. Noninvasive thermal ablation of hepatocellular carcinoma by using magnetic resonance imaging-guided focused ultrasound. Gastroenterology. 2004 Nov;127(5 Suppl 1):S242-7. Review. PubMed PMID: 15508090.

90: Hynynen K, McDannold N. MRI guided and monitored focused ultrasound thermal ablation methods: a review of progress. Int J Hyperthermia. 2004 Nov;20(7):725-37. Review. PubMed PMID: 15675668.

91: Clement GT. Perspectives in clinical uses of high-intensity focused ultrasound. Ultrasonics. 2004 Aug;42(10):1087-93. PubMed PMID: 15234170.

92: Hynynen K, Clement GT, McDannold N, Vykhodtseva N, King R, White PJ, Vitek S, Jolesz FA. 500-element ultrasound phased array system for noninvasive focal surgery of the brain: a preliminary rabbit study with ex vivo human skulls. Magn Reson Med. 2004 Jul;52(1):100-7. PubMed PMID: 15236372.

93: Sheikov N, McDannold N, Vykhodtseva N, Jolesz F, Hynynen K. Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles. Ultrasound Med Biol. 2004 Jul;30(7):979-89. PubMed PMID: 15313330.

94: McDannold N, King RL, Hynynen K. MRI monitoring of heating produced by ultrasound absorption in the skull: in vivo study in pigs. Magn Reson Med. 2004 May;51(5):1061-5. PubMed PMID: 15122691.

95: McDannold N, Vykhodtseva N, Jolesz FA, Hynynen K. MRI investigation of the threshold for thermally induced blood-brain barrier disruption and brain tissue damage in the rabbit brain. Magn Reson Med. 2004 May;51(5):913-23. PubMed PMID: 15122673.

96: Clement GT, White PJ, Hynynen K. Enhanced ultrasound transmission through the human skull using shear mode conversion. J Acoust Soc Am. 2004 Mar;115(3):1356-64. PubMed PMID: 15058357.

97: McDannold N, Fossheim SL, Rasmussen H, Martin H, Vykhodtseva N, Hynynen K. Heat-activated liposomal MR contrast agent: initial in vivo results in rabbit liver and kidney. Radiology. 2004 Mar;230(3):743-52. Epub 2004 Feb 5. PubMed PMID: 14764890.

98: Clement GT, Hynynen K. Forward planar projection through layered media. IEEE Trans Ultrason Ferroelectr Freq Control. 2003 Dec;50(12):1689-98. PubMed PMID: 14761040.

99: McDannold N, Moss M, Killiany R, Rosene DL, King RL, Jolesz FA, Hynynen K. MRI-guided focused ultrasound surgery in the brain: tests in a primate model. Magn Reson Med. 2003 Jun;49(6):1188-91. PubMed PMID: 12768598.

100: Tempany CM, Stewart EA, McDannold N, Quade BJ, Jolesz FA, Hynynen K. MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study. Radiology. 2003 Mar;226(3):897-905. PubMed PMID: 12616023.

101: Hynynen K, McDannold N, Martin H, Jolesz FA, Vykhodtseva N. The threshold for brain damage in rabbits induced by bursts of ultrasound in the presence of an ultrasound contrast agent (Optison). Ultrasound Med Biol. 2003 Mar;29(3):473-81. PubMed PMID: 12706199.

102: King RL, Clement GT, Maruvada S, Hynynen K. Preliminary results using ultrasound transmission for image-guided thermal therapy. Ultrasound Med Biol. 2003 Feb;29(2):293-9. PubMed PMID: 12659917.

103: Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA. Non-invasive opening of BBB by focused ultrasound. Acta Neurochir Suppl. 2003;86:555-8. PubMed PMID: 14753505.

104: Connor CW, Clement GT, Hynynen K. A unified model for the speed of sound in cranial bone based on genetic algorithm optimization. Phys Med Biol. 2002 Nov 21;47(22):3925-44. PubMed PMID: 12476974.

105: Jolesz FA, Talos IF, Schwartz RB, Mamata H, Kacher DF, Hynynen K, McDannold N, Saivironporn P, Zao L. Intraoperative magnetic resonance imaging and magnetic resonance imaging-guided therapy for brain tumors. Neuroimaging Clin N Am. 2002 Nov;12(4):665-83. Review. PubMed PMID: 12687918.

106: Clement GT, Hynynen K. Correlation of ultrasound phase with physical skull properties. Ultrasound Med Biol. 2002 May;28(5):617-24. PubMed PMID: 12079698.

107: Clement GT, Hynynen K. A non-invasive method for focusing ultrasound through the human skull. Phys Med Biol. 2002 Apr 21;47(8):1219-36. PubMed PMID: 12030552.

108: Clement GT, Hynynen K. Micro-receiver guided transcranial beam steering. IEEE Trans Ultrason Ferroelectr Freq Control. 2002 Apr;49(4):447-53. PubMed PMID: 11989700.

109: McDannold N, King RL, Jolesz FA, Hynynen K. The use of quantitative temperature images to predict the optimal power for focused ultrasound surgery: in vivo verification in rabbit muscle and brain. Med Phys. 2002 Mar;29(3):356-65. PubMed PMID: 11929019.

110: Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA. Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits. Radiology. 2001 Sep;220(3):640-6. PubMed PMID: 11526261.

111: Mahoney K, Fjield T, Mcdannold N, Clement G, Hynynen K. Comparison of modelled and observed in vivo temperature elevations induced by focused ultrasound: implications for treatment planning. Phys Med Biol. 2001 Jul;46(7):1785-98. PubMed PMID: 11474925.

112: Hynynen K, Pomeroy O, Smith DN, Huber PE, McDannold NJ, Kettenbach J, Baum J, Singer S, Jolesz FA. MR imaging-guided focused ultrasound surgery of fibroadenomas in the breast: a feasibility study. Radiology. 2001 Apr;219(1):176-85. PubMed PMID: 11274554.

113: McDannold N, Hynynen K, Jolesz F. MRI monitoring of the thermal ablation of tissue: effects of long exposure times. J Magn Reson Imaging. 2001 Mar;13(3):421-7. PubMed PMID: 11241817.

114: McDannold N, Hynynen K, Oshio K, Mulkern RV. Temperature monitoring with line scan echo planar spectroscopic imaging. Med Phys. 2001 Mar;28(3):346-55. PubMed PMID: 11318316.

115: Clement GT, Sun J, Hynynen K. The role of internal reflection in transskull phase distortion. Ultrasonics. 2001 Mar;39(2):109-13. PubMed PMID: 11270628.

116: Vykhodtseva N, McDannold N, Martin H, Bronson RT, Hynynen K. Apoptosis in ultrasound-produced threshold lesions in the rabbit brain. Ultrasound Med Biol. 2001 Jan;27(1):111-7. PubMed PMID: 11295277.

117: Clement GT, Sun J, Giesecke T, Hynynen K. A hemisphere array for non-invasive ultrasound brain therapy and surgery. Phys Med Biol. 2000 Dec;45(12):3707-19. PubMed PMID: 11131194.

118: McDannold NJ, King RL, Jolesz FA, Hynynen KH. Usefulness of MR imaging-derived thermometry and dosimetry in determining the threshold for tissue damage induced by thermal surgery in rabbits. Radiology. 2000 Aug;216(2):517-23. PubMed PMID: 10924580.

119: Clement GT, Hynynen K. Field characterization of therapeutic ultrasound phased arrays through forward and backward planar projection. J Acoust Soc Am. 2000 Jul;108(1):441-6. PubMed PMID: 10923906.

120: Hynynen K, McDannold N, Mulkern RV, Jolesz FA. Temperature monitoring in fat with MRI. Magn Reson Med. 2000 Jun;43(6):901-4. PubMed PMID: 10861887.

121: McDannold NJ, Jolesz FA. Magnetic resonance image-guided thermal ablations. Top Magn Reson Imaging. 2000 Jun;11(3):191-202. Review. PubMed PMID: 11145211.

122: Clement GT, White J, Hynynen K. Investigation of a large-area phased array for focused ultrasound surgery through the skull. Phys Med Biol. 2000 Apr;45(4):1071-83. PubMed PMID: 10795992.

123: McDannold NJ, Jolesz FA, Hynynen KH. Determination of the optimal delay between sonications during focused ultrasound surgery in rabbits by using MR imaging to monitor thermal buildup in vivo. Radiology. 1999 May;211(2):419-26. PubMed PMID: 10228523.

124: Sharf Y, Clement GT, Hynynen K. Absolute measurements of ultrasonic pressure by using high magnetic fields. IEEE Trans Ultrason Ferroelectr Freq Control. 1999;46(6):1504-11. doi: 10.1109/58.808874. PubMed PMID: 18244347.

125: Foldes K, Hynynen K, Shortkroff S, Winalski CS, Collucci V, Koskinen SK, McDannold N, Jolesz F. Magnetic resonance imaging-guided focused ultrasound synovectomy. Scand J Rheumatol. 1999;28(4):233-7. PubMed PMID: 10503560.

126: Mulkern RV, Panych LP, McDannold NJ, Jolesz FA, Hynynen K. Tissue temperature monitoring with multiple gradient-echo imaging sequences. J Magn Reson Imaging. 1998 Mar-Apr;8(2):493-502. PubMed PMID: 9562081.