Focused Ultrasound Laboratory

Internal

Announcements 

Lab Meetings
(2PM, LMRC 522) 

1/01: No Meeting
1/08: No Meeting
1/15: Nathan McDannold (Research Update)
1/22: General Meeting
1/29: Tao Sun (Journal Club)

2/05: Nick Todd (Research Update)
2/12: General Meeting
2/19: General Meeting
2/26: Tiago Ribeiro (Journal Club)

3/04: No Meeting
3/11: Tao Sun (Research Update) 
3/18: General Meeting
3/25: Chengaung Peng (Journal Club) 

4/01: Tiago Ribeiro (Research Update) 
4/08: General Meeting
4/15: General Meeting
4/22: General Meeting
4/29: Nick Todd (Journal Club)

5/06: Chengaung Peng (Research Update)
5/13: General Meeting
5/20: General Meeting
5/27: TBD

Research Training

  1. Lab Safety Orientation. Before any work can be performed within the FUS Lab facilities, all new research personnel must make an appointment with the Safety Officer (Yui Power, cpower at bwh.harvard.edu) for a lab safety orientation. 
  2. Setting up a Partners User Account. Go to https://myprofile.partners.org. Click on “New User Registration”. Complete the process by following the on-screen instructions. FAQ: http://helpdesk.partners.org/passwordselfservice. Help desk: (617) 732-5927.
  3. MRI safety training. required for all research personnel who will be working either indirectly (e.g., observing) or directly with MRI scanners. If you anticipate that your project will require some level of work with MRI, please be sure to attend a training session by making arrangements with Vera Kimbrell (VKIMBRELL at PARTNERS.ORG).
  4. Animal Research Training. As per BWH IACUC policy, all researchers using animals must complete appropriate courses on the humane care and use of laboratory animals. Log into this site and follow instructions for training through the AALAS Learning Library: animal.bwh.harvard.edu
  5. CITI course in the protection of human subjects. This training is required of all personnel engaged in projects with human volunteers or patients. In addition, a refresher course is required every 2 years. These courses are Internet-based. For more information, see www.citiprogram.org.

Lab Safety
General Hazards

  • Food and/or drinks are not allowed in the labs or the machine shop.
  • Shorts, skirts, and/or open-toed shoes are not allowed in the labs or the machine shop.
  • Loose clothing (lab coats, long sleeves, ties, etc.), loose jewelry, loose long hair, and/or unrestrained ID badges are not allowed in the machine shop.
  • Discard needles, injection pipettes, razor blades, etc. in sharps containers. Do not recap needles.
  • Dispose of broken glass in the broken-glass container.
  • Clean up spills appropriately and promptly. Chemical spill kits are next to the fume hood in room 514. Water “spill kits” (mops and towels) are next to the large file cabinet in rom 519.
  • Appropriate personal protective equipment (PPE) must be used when working with chemical hazards, biological hazards, and/or physical hazards.
  • Compressed gas cylinders (empty or full) must be stored securely upright. Cylinders should never be dropped or allowed to strike each other with force. Transport compressed gas cylinders with protective caps in place and do not roll or drag the cylinders.
  • Any work-related injuries must be reported and documented within 24-hours of the incident. If you are not a BWH employee, report to Emergency Services. If you are a BWH employee, you can contact Occupational Health Services (OHS) at (617) 732-6034. If OHS is closed, report to Emergency Services and follow-up with OHS when it is next open.
  • All personnel must evacuate the building during a fire emergency alarm situation.

Chemical Hazards

  • Material Safety Data Sheets (MSDS) and our lab’s Chemical Hygiene Plan (CHP) are kept on the shelf next to the fume hood in room 514.
  • Upon obtaining new chemicals, there are two steps that must be taken for the lab to be compliant with OSHA standards for chemical usage in a laboratory. First, an MSDS must be procured and included in the MSDS folder on the shelf next to the fume hood. Second, the chemical inventory sheet (in a folder next to the MSDS folder) must be updated. These steps are the responsibility of the investigator who ordered the chemical. Chemicals with numeric prefixes (e.g., 2-Propanol and 1-Butanol) are filed under the name of the substance, not the number.
  • Hazardous waste must be placed in the satellite accumulation area (SAA) in room 514 (next to the fume hood) and must be properly labeled with the official tags (these can be found at the SAA). The investigator must then complete an online request for pickup. This link to the BWH Department of Environmental Affairs provides information about hazardous chemical waste disposal and the pickup request form: 
    https://docs.google.com/forms/d/1HfCW4QO-4qBZ8hFswYNXJxIJ3CEemFSlQPgJdOyocrg/viewform?embedded=true&formkey=dGx4Tk9SdUxtYUtIdncxeHM0Uko0OGc6MA

Biological Hazards

  • Research specimens in the cold room, refrigerator, and/or freezer must be contained in a sealed, leak-proof container, and labeled with a content description, date, and the researcher’s name. DO NOT forget about items left in refrigeration; please discard them (appropriately) when they are no longer needed.
  • Tissue fixed in formalin must be stored in screw-top containers and labeled properly (tissue type, investigator name, and date). Do not use containers with snap-on lids.

 Directions

  • AMIGO SUITE: (1) From the Main Entrance (75 Francis Street) Take the Amory Elevators to L2, Take a left off the elevators and then take an immediate left, Go down the hall and take of another set of double doors. You will see a small black camera and a sign that say’s AMIGO on the wall to the right. Press Button on camera for entrance. (2) From 70 Francis Street (aka Shapiro building), Take back set of elevators to L2 (not front set of elevators), Take a left off elevators and go though the door (switch plate on wall), Take an immediate right and follow the hallway half way down and just past the double doors on the right your will see L2 Echocardiogram Lab. We are directly across from this. Please notice that there is a a small black camera and a sign that say’s AMIGO. Press Button on camera for entrance.
  • ANESTHESIA CONFERENCE ROOM: Enter at 75 Francis Street (Brigham and Women’s Hospital Main Entrance) through the revolving doors. Go to your right walk towards armory elevators. Take these elevators down to L1. Take a right off the elevators, and walk down the hallway take your first left. Walk to the end of the hallway and take right. Take an immediate left, walk past the elevators and take a right at the vending machine. Around the corner on your left you will see a set of double doors; this is the
    Anesthesia Conference Room.
  • ARMENISE AMPHITHEATER: When facing HMS on Longwood Avenue, the entrance to Armenise is on the left side, half way towards the back of the quad. You will find signs hanging up on the entrance door and windows along the route. Go through the door, and turn left. The auditorium is just passed the elevators, only a short distance down the hallway.
  • ABRAMS CONFERENCE ROOM: The Abrams Conference room is located on the L1 level of Brigham and Women’s Hospital. (1) From the Main Entrance (75 Francis Street), turn right as you enter the building. Take the Amory Elevator down one floor to L1. Make a right turn as you exit the elevator. The Abrams conference Room is down the hall on the left. (2) From the Ambulatory Services Entrance (45 Francis Street), turn left as you enter the building from outside. Take the Nesson Ambulatory Elevator (NOT the Parking Elevator) down two floors to L1. Make a right turn as you exit the elevator. Turn right at the first corner and right at the next. The conference room is down the hall on the right.
  • BORNSTEIN AMPHITHEATER: Located on the 2nd Floor “Pike” in Brigham and Women’s Hospital. From main lobby on the 1st floor at 75 Francis Street, walk down the “lower pike” corridor to the Connors Center for Women’s Health elevators. Take the elevator up one level. Turn left into the main corridor. Find the entrance to this room on your left, between exits 5 and 6.
  • CARRIE HALL: It is located in the main Hospital Building at 15 Francis Street. The section of the building is called “Peter Bent Brigham.” Go in through the rotating door; in front of you you’ll see a security guard; facing the guard, turn to your right; walk all the way down that hallway. You will walk straight into Carrie Hall.
  • DUNCAN REID CONFERENCE ROOM: Enter through the hospital’s 75 Francis Street entrance. Take the main staircase, located at the back right of the lobby, one flight to the second floor. Turn left, at the top of the staircase, onto the second floor hallway, the Pike. Take your first right (exit 3) off the pike, proceed pass the elevators. Take your first right. The Duncan Reid conference room will be at the end of this hallway, directly in front of you.
  • HOLLENBERG CONFERENCE ROOM: The Hollenberg Conference Room is on the 3rd Floor of the Thorn Building, room 316. The Thorn Building is between exits 6 and 7 on the Pike. When you get off the elevator, the conference room will be directly in front of you, but you will need to go around the corner to the left, to the entrance.
  • LEE BELL CENTER FOR BREAST IMAGING: Located in the Connors Center for Women’s Health on the second level. From the Main Entrance at 75 Francis Street, turn right inside the building and walk toward the Gift Shop. You will see a stairway to your left. Take the stairs to the second floor. Turn left at the top of the stairs. The Connors Center will be on your left after you pass through the double doors (these doors are usually open). Take the hallway to the left, toward the bridge to Children’s Hospital. Breast Imaging Diagnostic Center is on the left.
  • ONE BRIGHAM CIRCLE: This is the building by JP Licks and ‘Stop & Shop.’ It is on the other side of Huntington Avenue from the main hospital building. The street address is 1620 Tremont Street. When you enter the building, go through the Brigham and Women’s double doors on your left.
  • RAMZI COTRAN CONFERENCE CENTER: Inside the main entrance/lobby of the Brigham and Women’s Hospital at 75 Francis Street (the Amory Laboratory Building), you will see a bank of elevators and an escalator. Take the Amory elevators to the 3rd floor. On the 3rd floor, turn right off the elevators. The entrance to “The Ramzi Cotran Conference Center” is well-marked and is the first set of double doors on the right (Amory 360.F.1, BWH Pathology).
  • SURGICAL PLANNING LABORATORY: Once you are inside the Brigham’s main lobby, take the Amory elevators across from the information desk down to L1. When you leave the elevators, turn right. Walk down the hallway: the third door on your right is marked SPL.
  • ZINNER BOARDROOM: Coming from 75 Francis, on the Pike, walk over bridge into Shapiro Building, take escalators or elevators to first floor, walk towards back, left side of building, take right through double glass doors, entrance to room through double doors straight ahead.
  • ZINNER BREAKOUT ROOM: Coming from 75 Francis, on the Pike, walk over bridge into Shapiro Building, take escalators or elevators to first floor, walk towards back, left side of building, take right through double glass doors, entrance to room through double doors on left. (Room# 70FR-1010)